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PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1

Summary: Pancreatic progenitor cell differentiation and proliferation factor (PPDPF) has been reported to play a role in tumorigenesis. However, its function in hepatocellular carcinoma (HCC) remains poorly understood. In this study, we report that PPDPF is significantly downregulated in HCC and the...

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Bibliographic Details
Main Authors: Yi-Kang Wang, Ning Ma, Sheng Xu, Jing-Yi Huang, Qian-Zhi Ni, Hui-Jun Cao, Qian-Wen Zheng, Bing Zhu, Ji Xia, Feng-Kun Zhang, Xu-Fen Ding, Xiao-Song Qiu, Tian-Wei Chen, Kang Wang, Wei Chen, Zhi-Gang Li, Shu-Qun Cheng, Dong Xie, Jing-Jing Li
Format: Artigo
Language:Inglês
Published: Elsevier 2023-04-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003510
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