Efficient Synthesis of α-Branched Purine-Based Acyclic Nucleosides: Scopes and Limitations of the Method

An efficient route to acylated acyclic nucleosides containing a branched hemiaminal ether moiety is reported via three-component alkylation of <i>N</i>-heterocycle (purine nucleobase) with acetal (cyclic or acyclic, variously branched) and anhydride (preferentially acetic anhydride). The procedure e...

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Главные авторы:	Jan Frydrych, Lenka Poštová Slavětínská, Martin Dračínský, Zlatko Janeba
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2020-09-01
Серии:	Molecules
Предметы:	acyclonucleosides hemiaminal ether purine multi-component reaction
Online-ссылка:	https://www.mdpi.com/1420-3049/25/18/4307
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