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Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo

Brains depend on blood flow for the delivery of oxygen and nutrients essential for proper neuronal and synaptic functioning. French physiologist Rouget was the first to describe pericytes in 1873 as regularly arranged longitudinal amoeboid cells on capillaries that have a muscular coat, implying tha...

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Bibliografiske detaljer
Principais autores: Amy R. Nelson, Meghana A. Sagare, Yaoming Wang, Kassandra Kisler, Zhen Zhao, Berislav V. Zlokovic
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-04-01
Serier:Frontiers in Aging Neuroscience
Fag:
Online adgang:https://www.frontiersin.org/article/10.3389/fnagi.2020.00108/full
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