Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo

Brains depend on blood flow for the delivery of oxygen and nutrients essential for proper neuronal and synaptic functioning. French physiologist Rouget was the first to describe pericytes in 1873 as regularly arranged longitudinal amoeboid cells on capillaries that have a muscular coat, implying tha...

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Hlavní autoři:	Amy R. Nelson, Meghana A. Sagare, Yaoming Wang, Kassandra Kisler, Zhen Zhao, Berislav V. Zlokovic
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-04-01
Edice:	Frontiers in Aging Neuroscience
Témata:	pericyte optogenetics channelrhodopsin brain capillaries red blood cell capillary flow
On-line přístup:	https://www.frontiersin.org/article/10.3389/fnagi.2020.00108/full
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