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A DFT study of the gallium ion-binding capacity of mature Pseudomonas aeruginosa biofilm extracellular polysaccharide.

Intravenous gallium therapy is a non-antibiotic approach to limit Pseudomonas aeruginosa biofilm proliferation, by outcompeting iron for siderophore binding. Gallium therapy represents a viable therapeutic strategy for cystic fibrosis (CF) patients harbouring mucoid P. aeruginosa biofilm lung infect...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Oliver J Hills, Zuzanna Poskrobko, Andrew J Scott, James Smith, Helen F Chappell
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2023-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0287191
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