Increased levels and activation of the IL-17 receptor in microglia contribute to enhanced neuroinflammation in cerebellum of hyperammonemic rats

Abstract Background Patients with liver cirrhosis may show minimal hepatic encephalopathy (MHE) with mild cognitive impairment and motor incoordination. Rats with chronic hyperammonemia reproduce these alterations. Motor incoordination in hyperammonemic rats is due to increased GABAergic neurotransm...

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Autori principali:	Yaiza M. Arenas, Adrià López-Gramaje, Carmina Montoliu, Marta Llansola, Vicente Felipo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-04-01
Serie:	Biological Research
Soggetti:	Cerebellum Hyperammonemia IL-17 Neuroinflammation Microglia Hepatic encephalopathy
Accesso online:	https://doi.org/10.1186/s40659-024-00504-2
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