Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines

Adolescent synaptic pruning is thought to enable optimal cognition because it is disrupted in certain neuropathologies, yet the initiator of this process is unknown. One factor not yet considered is the α4βδ GABAA receptor (GABAR), an extrasynaptic inhibitory receptor which first emerges on dendriti...

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Autors principals:	Sonia Afroz, Julie Parato, Hui Shen, Sheryl Sue Smith
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2016-05-01
Col·lecció:	eLife
Matèries:	GABA-A receptor hippocampus puberty dendritic spine synaptic pruning delta
Accés en línia:	https://elifesciences.org/articles/15106
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