Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines

Adolescent synaptic pruning is thought to enable optimal cognition because it is disrupted in certain neuropathologies, yet the initiator of this process is unknown. One factor not yet considered is the α4βδ GABAA receptor (GABAR), an extrasynaptic inhibitory receptor which first emerges on dendriti...

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Autores principales:	Sonia Afroz, Julie Parato, Hui Shen, Sheryl Sue Smith
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2016-05-01
Colección:	eLife
Materias:	GABA-A receptor hippocampus puberty dendritic spine synaptic pruning delta
Acceso en línea:	https://elifesciences.org/articles/15106
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