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Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia caused by accumulation of multiple genetic alterations in T-cell progenitors. However, for many genes it remains unknown how their mutations contribute to disease development. Therefore, we performed two single-cell CRISP...

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Bibliografski detalji
Glavni autori: Sarah Meyers, Olga Gielen, Jan Cools, Sofie Demeyer
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2024-05-01
Serija:Haematologica
Online pristup:https://haematologica.org/article/view/11621
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