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Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia caused by accumulation of multiple genetic alterations in T-cell progenitors. However, for many genes it remains unknown how their mutations contribute to disease development. Therefore, we performed two single-cell CRISP...

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Detalhes bibliográficos
Principais autores: Sarah Meyers, Olga Gielen, Jan Cools, Sofie Demeyer
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2024-05-01
coleção:Haematologica
Acesso em linha:https://haematologica.org/article/view/11621
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