Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity

Abstract Deep brain stimulation has been used to treat severe, refractory obsessive-compulsive disorder (OCD) with variable outcomes across multiple anatomical targets. To overcome these limitations, we developed an invasive brain mapping paradigm in which electrodes were implanted across the OCD co...

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主要な著者:	A. Moses Lee, Audrey Kist, John Alvarez, Kristin K. Sellers, Ankit N. Khambhati, Leo P. Sugrue, Lee B. Reid, Kelly Kadlec, Sneha Ray, Joline M. Fan, Anusha B. Allawala, Caroline A. Racine, Tenzin Norbu, Dani Astudillo, Alexandra G. Tremblay-McGaw, Natalie Becker, Jessica Verhein, Ahmad Alhourani, Philip A. Starr, Edward F. Chang, Andrew D. Krystal
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Publishing Group 2025-10-01
シリーズ:	Translational Psychiatry
オンライン･アクセス:	https://doi.org/10.1038/s41398-025-03690-z
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