Towards Facile Radiolabeling and Preparation of Gallium-68-/Bismuth-213-DOTA-[Thi⁸, Met(O₂)¹¹]-Substance P for Future Clinical Application: First Experiences

Substance P (SP) is a small peptide commonly known as a preferential endogenous ligand for the transmembrane neurokinin-1 receptor. Nuclear Medicine procedures currently involve radiolabeled SP derivatives in peptide radioligand endotherapy of inoperable glioblastoma. Promising clinical results spar...

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Principais autores:	Janine Suthiram, Thomas Ebenhan, Biljana Marjanovic-Painter, Mike M. Sathekge, Jan Rijn Zeevaart
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-08-01
coleção:	Pharmaceutics
Assuntos:	gallium-68 <sup>68</sup>Ge/<sup>68</sup>Ga generator kit preparation DOTA DOTA-Substance P [<sup>68</sup>Ga]Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-[Thi<sup>8</sup>, Met(O<sub>2</sub>)<sup>11</sup>]-Substance-P
Acesso em linha:	https://www.mdpi.com/1999-4923/13/9/1326
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