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Towards Facile Radiolabeling and Preparation of Gallium-68-/Bismuth-213-DOTA-[Thi<sup>8</sup>, Met(O<sub>2</sub>)<sup>11</sup>]-Substance P for Future Clinical Application: First Experiences

Substance P (SP) is a small peptide commonly known as a preferential endogenous ligand for the transmembrane neurokinin-1 receptor. Nuclear Medicine procedures currently involve radiolabeled SP derivatives in peptide radioligand endotherapy of inoperable glioblastoma. Promising clinical results spar...

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Autores principales: Janine Suthiram, Thomas Ebenhan, Biljana Marjanovic-Painter, Mike M. Sathekge, Jan Rijn Zeevaart
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2021-08-01
Colección:Pharmaceutics
Materias:
gallium-68
<sup>68</sup>Ge/<sup>68</sup>Ga generator
kit preparation
DOTA
DOTA-Substance P
[<sup>68</sup>Ga]Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-[Thi<sup>8</sup>, Met(O<sub>2</sub>)<sup>11</sup>]-Substance-P
Acceso en línea:https://www.mdpi.com/1999-4923/13/9/1326
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