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Acetylation-Mediated Post-Translational Modification of Pyruvate Dehydrogenase Plays a Critical Role in the Regulation of the Cellular Acetylome During Metabolic Stress

<b>Background:</b> Cardiac diseases remain one of the leading causes of death globally, often linked to ischemic conditions that can affect cellular homeostasis and metabolism, which can lead to the development of cardiovascular dysfunction. Considering the effect of ischemic cardiomyopathy on the g...

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Principais autores: Aishwarya Rajakumar, Sarah Nguyen, Nicole Ford, Gbenga Ogundipe, Ethan Lopez-Nowak, Olena Kondrachuk, Manish K Gupta
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-12-01
Serier:Metabolites
Fag:
acetylation
ischemia
pyruvate dehydrogenase complex
cardiomyocytes
post-translational modification
metabolism
Online adgang:https://www.mdpi.com/2218-1989/14/12/701
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