Acetylation-Mediated Post-Translational Modification of Pyruvate Dehydrogenase Plays a Critical Role in the Regulation of the Cellular Acetylome During Metabolic Stress

<b>Background:</b> Cardiac diseases remain one of the leading causes of death globally, often linked to ischemic conditions that can affect cellular homeostasis and metabolism, which can lead to the development of cardiovascular dysfunction. Considering the effect of ischemic cardiomyopathy on the g...

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Autori principali:	Aishwarya Rajakumar, Sarah Nguyen, Nicole Ford, Gbenga Ogundipe, Ethan Lopez-Nowak, Olena Kondrachuk, Manish K Gupta
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-12-01
Serie:	Metabolites
Soggetti:	acetylation ischemia pyruvate dehydrogenase complex cardiomyocytes post-translational modification metabolism
Accesso online:	https://www.mdpi.com/2218-1989/14/12/701
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