Synthesis, Antibacterial Properties and Molecular Docking Studies of Nitrogen Substituted 9-(((4X-But-2-ynyloxy)methyl)-1,2,3-triazolyl)–Cinchona Alkaloid Conjugates

The year 2024 marked the 80th anniversary of Woodward’s total synthesis of quinine. Quinine is a natural alkaloid from the bark of the cinchona tree that has been used for years as an antimalarial drug. The antibacterial effect of quinine salts has also been regarded. With this in mind, a series of...

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Autori principali:	Gulim K. Mukusheva, Nurizat N. Toigambekova, Victor A. Savelyev, Andrey I. Khlebnikov, Liubov G. Burova, Sofiia D. Afanaseva, Oralgazy A. Nurkenov, Anarkul S. Kishkentayeva, Aikerim S. Olzhabayeva, Yurii V. Gatilov, Roza B. Seidakhmetova, Alexander N. Evstropov, Elvira E. Shults
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-11-01
Serie:	Molecules
Soggetti:	cinchona alkaloids quinine triazoles A<sup>3</sup>-coupling reactions antibacterial activity bacterial biofilms
Accesso online:	https://www.mdpi.com/1420-3049/30/22/4352
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