Noncanonical Expression of a Murine Cytomegalovirus Early Protein CD8 T-Cell Epitope as an Immediate Early Epitope Based on Transcription from an Upstream Gene

Viral CD8 T-cell epitopes, represented by viral peptides bound to major histocompatibility complex class-I (MHC-I) glycoproteins, are often identified by “reverse immunology”, a strategy not requiring biochemical and structural knowledge of the actual viral protein from which they are derived by ant...

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Autors principals:	Annette Fink, Julia K. Büttner, Doris Thomas, Rafaela Holtappels, Matthias J. Reddehase, Niels A. W. Lemmermann
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2014-02-01
Col·lecció:	Viruses
Matèries:	antigenic peptides antigen presentation CD8 T cell epitope gene expression immediate-early protein murine CMV ORF m164 open reading frame RACE mapping reverse immunology transcription start site translation start site
Accés en línia:	http://www.mdpi.com/1999-4915/6/2/808
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