Broad-Based Influenza-Specific CD8⁺ T Cell Response without the Typical Immunodominance Hierarchy and Its Potential Implication

Syngeneic murine systems have pre-fixed MHC, making them an imperfect model for investigating the impact of MHC polymorphism on immunodominance in influenza A virus (IAV) infections. To date, there are few studies focusing on MHC allelic differences and its impact on immunodominance even though it i...

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Библиографические подробности

Главные авторы:	Miaojuan Huang, Rong Xu, Cristina Triffon, Nicole Mifsud, Weisan Chen
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-06-01
Серии:	Viruses
Предметы:	influenza A virus HLA antigen presentation CD8<sup>+</sup> T cell epitope immunodominance
Online-ссылка:	https://www.mdpi.com/1999-4915/13/6/1080
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