Broad-Based Influenza-Specific CD8⁺ T Cell Response without the Typical Immunodominance Hierarchy and Its Potential Implication

Syngeneic murine systems have pre-fixed MHC, making them an imperfect model for investigating the impact of MHC polymorphism on immunodominance in influenza A virus (IAV) infections. To date, there are few studies focusing on MHC allelic differences and its impact on immunodominance even though it i...

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Detalles Bibliográficos

Autores principales:	Miaojuan Huang, Rong Xu, Cristina Triffon, Nicole Mifsud, Weisan Chen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2021-06-01
Colección:	Viruses
Materias:	influenza A virus HLA antigen presentation CD8<sup>+</sup> T cell epitope immunodominance
Acceso en línea:	https://www.mdpi.com/1999-4915/13/6/1080
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