Inverse-Folding Design of Yeast Telomerase RNA Increases Activity In Vitro
<i>Saccharomyces cerevisiae</i> telomerase RNA, TLC1, is an 1157 nt non-coding RNA that functions as both a template for DNA synthesis and a flexible scaffold for telomerase RNP holoenzyme protein subunits. The tractable budding yeast system has provided landmark discoveries about telomere biology i...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2023-08-01
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| Schriftenreihe: | Non-Coding RNA |
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| Online-Zugang: | https://www.mdpi.com/2311-553X/9/5/51 |
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