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Inverse-Folding Design of Yeast Telomerase RNA Increases Activity In Vitro

<i>Saccharomyces cerevisiae</i> telomerase RNA, TLC1, is an 1157 nt non-coding RNA that functions as both a template for DNA synthesis and a flexible scaffold for telomerase RNP holoenzyme protein subunits. The tractable budding yeast system has provided landmark discoveries about telomere biology i...

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Principais autores: Kevin J. Lebo, David C. Zappulla
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-08-01
Series:Non-Coding RNA
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Acceso en liña:https://www.mdpi.com/2311-553X/9/5/51
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