Genetic variations of EBV-LMP1 from nasopharyngeal carcinoma biopsies: potential loss of T cell epitopes

To find Epstein-Barr virus (EBV) strains with genetic variations of EBV latent membrane protein 1 (EBV-LMP1) from nasopharyngeal carcinoma (NPC), the full-length DNA of LMP1 genes from 21 NPC biopsies obtained in Hunan province in southern China was amplified and sequenced. Our sequences were compar...

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Detalhes bibliográficos

Principais autores:	Y.L. Tang, J.H. Lu, L. Cao, M.H. Wu, S.P. Peng, H.D. Zhou, C. Huang, Y.X. Yang, Y.H. Zhou, Q. Chen, X.L. Li, M. Zhou, G.Y. Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Associação Brasileira de Divulgação Científica 2008-02-01
coleção:	Brazilian Journal of Medical and Biological Research
Assuntos:	Genetic variation Epitope Immune recognition Latent membrane protein 1 Tumorigenicity
Acesso em linha:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000200006
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