EBV‐LMP1 induces APOBEC3s and mitochondrial DNA hypermutation in nasopharyngeal cancer

Abstract An Epstein‐Barr virus (EBV)—encoded latent membrane protein 1 (LMP1) is a principal oncogene that plays a pivotal role in EBV‐associated malignant tumors including nasopharyngeal cancer (NPC). Recent genomic landscape studies revealed that NPC also contained many genomic mutations, suggesti...

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Detalles Bibliográficos

Principais autores:	Kousho Wakae, Satoru Kondo, Hai Thanh Pham, Naohiro Wakisaka, Lusheng Que, Yingfang Li, Xin Zheng, Kento Fukano, Kouichi Kitamura, Koichi Watashi, Hideki Aizaki, Takayoshi Ueno, Makiko Moriyama‐Kita, Kazuya Ishikawa, Yosuke Nakanishi, Kazuhira Endo, Masamichi Muramatsu, Tomokazu Yoshizaki
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2020-10-01
Series:	Cancer Medicine
Assuntos:	APOBEC EBV‐LMP1 mitochondrial DNA nasopharyngeal cancer
Acceso en liña:	https://doi.org/10.1002/cam4.3357
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