Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of <italic toggle="yes">Klebsiella pneumoniae</italic> Carbapenemase-Carrying Plasmids

ABSTRACT The rapid dissemination of antimicrobial resistance (AMR) around the globe is largely due to mobile genetic elements, such as plasmids. They confer resistance to critically important drugs, including extended-spectrum beta-lactams, carbapenems, and colistin. Large, complex resistance plasmi...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Michelle M. C. Buckner, Howard T. H. Saw, Rachael N. Osagie, Alan McNally, Vito Ricci, Matthew E. Wand, Neil Woodford, Alasdair Ivens, Mark A. Webber, Laura J. V. Piddock
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	American Society for Microbiology 2018-05-01
Rangatū:	mBio
Ngā marau:	fitness Klebsiella pneumoniae carbapenemase (KPC) genome pKpQIL plasmid transcriptome
Urunga tuihono:	https://journals.asm.org/doi/10.1128/mBio.02303-17
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!