Optical genome mapping reveals a recurrent translocation, t(14;16), in T/myeloid mixed phenotype acute leukemia: report of two cases

Abstract Background T/myeloid mixed-phenotype acute leukemias (MPAL-T/M) is a type of rare and high-risk acute leukemia that carries both T- and myeloid- lineage markers. The diagnosis of MPAL requires integration of clinical, immunophenotypic, and genetic information. Optical Genome Mapping (OGM) t...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Joanna Lum, Jessica Anderson-Calleja, Kimberly Van Dine, Emily Manion, Hong Xiao, Anamarija M. Perry, Daniel Boyer, Lina Shao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	Molecular Cytogenetics
Assuntos:	Optical genome mapping T/myeloid mixed-phenotype acute leukemia (MPAL-T/M) BCL11B enhancer hijacking
Acesso em linha:	https://doi.org/10.1186/s13039-026-00753-8
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!