Optical genome mapping reveals a recurrent translocation, t(14;16), in T/myeloid mixed phenotype acute leukemia: report of two cases

Abstract Background T/myeloid mixed-phenotype acute leukemias (MPAL-T/M) is a type of rare and high-risk acute leukemia that carries both T- and myeloid- lineage markers. The diagnosis of MPAL requires integration of clinical, immunophenotypic, and genetic information. Optical Genome Mapping (OGM) t...

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Auteurs principaux:	Joanna Lum, Jessica Anderson-Calleja, Kimberly Van Dine, Emily Manion, Hong Xiao, Anamarija M. Perry, Daniel Boyer, Lina Shao
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-02-01
Collection:	Molecular Cytogenetics
Sujets:	Optical genome mapping T/myeloid mixed-phenotype acute leukemia (MPAL-T/M) BCL11B enhancer hijacking
Accès en ligne:	https://doi.org/10.1186/s13039-026-00753-8
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