Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue

Human prepubertal testicular tissues are rare, but organ culture conditions to develop a system for human in vitro-spermatogenesis are an essential option for fertility preservation in prepubertal boys subjected to gonadotoxic therapy. To avoid animal testing in line with the 3Rs principle, organ cu...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Neels Lennart Aden, Matthias Bleeke, Uwe R. Kordes, Bianka Brunne, Barbara Holstermann, Ronald Biemann, Uta Ceglarek, Armin Soave, Andrea Salzbrunn, Stefan W. Schneider, Kathrein von Kopylow
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2023-01-01
Σειρά:	Cells
Θέματα:	prepubertal boys fertility preservation testis organ culture in vitro culture spermatogonia spermatogonial stem cells
Διαθέσιμο Online:	https://www.mdpi.com/2073-4409/12/3/415
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