Functional polymorphism of the mu-opioid receptor gene (OPRM1) influences reinforcement learning in humans.

Previous reports on the functional effects (i.e., gain or loss of function), and phenotypic outcomes (e.g., changes in addiction vulnerability and stress response) of a commonly occurring functional single nucleotide polymorphism (SNP) of the mu-opioid receptor (OPRM1 A118G) have been inconsistent....

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Main Authors: Mary R Lee, Courtney L Gallen, Xiaochu Zhang, Colin A Hodgkinson, David Goldman, Elliot A Stein, Christina S Barr
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0024203&type=printable
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