COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal
The COPI coat forms transport vesicles from the Golgi complex and plays a poorly defined role in endocytic trafficking. Here we show that COPI binds K63-linked polyubiquitin and this interaction is crucial for trafficking of a ubiquitinated yeast SNARE (Snc1). Snc1 is a v-SNARE that drives fusion of...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications Ltd
2017-10-01
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| Colección: | eLife |
| Materias: | |
| Acceso en línea: | https://elifesciences.org/articles/28342 |
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