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Early effects of ionizing radiation on molecular modifications and hallmarks of Immunogenic cell death in mouse tumor cells

Abstract Background Ionizing radiation (IR) is known to activate the immune system by releasing damage-associated molecular pattern (DAMP) molecules. To combine the IR with novel immunotherapies it is important to know how different irradiation doses influence the release of DAMPs and induce other m...

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Principais autores: Ursa Kesar, Bostjan Markelc, Maja Cemazar, Gregor Sersa, Tanja Jesenko, Primoz Strojan
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-02-01
Serier:BMC Cancer
Fag:
Ionizing radiation
Immune response
Immunogenic cell death
MHC i
MHC II
PD-L1
Online adgang:https://doi.org/10.1186/s12885-026-15674-3
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