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Early effects of ionizing radiation on molecular modifications and hallmarks of Immunogenic cell death in mouse tumor cells

Abstract Background Ionizing radiation (IR) is known to activate the immune system by releasing damage-associated molecular pattern (DAMP) molecules. To combine the IR with novel immunotherapies it is important to know how different irradiation doses influence the release of DAMPs and induce other m...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ursa Kesar, Bostjan Markelc, Maja Cemazar, Gregor Sersa, Tanja Jesenko, Primoz Strojan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-02-01
Schriftenreihe:BMC Cancer
Schlagworte:
Ionizing radiation
Immune response
Immunogenic cell death
MHC i
MHC II
PD-L1
Online-Zugang:https://doi.org/10.1186/s12885-026-15674-3
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