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Influence Mechanism of Drug–Polymer Compatibility on Humidity Stability of Crystalline Solid Dispersion

This study investigates the influence of humidity on the dissolution behavior and microstructure of drugs in crystalline solid dispersions (CSDs). Using Bifonazole (BFZ) as a model drug, CSDs were prepared through spray drying with carriers such as Poloxamer 188 (P188), Poloxamer 407 (P407), and pol...

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Détails bibliographiques
Auteurs principaux: Chunhui Hu, Qiuli Yan, Yong Zhang, Haiying Yan
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2023-11-01
Collection:Pharmaceuticals
Sujets:
Accès en ligne:https://www.mdpi.com/1424-8247/16/12/1640
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