Integrative machine learning of gene expression and DNA methylation for the accurate diagnosis of systemic lupus erythematosus and Sjögren’s syndrome

Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSjS) are systemic autoimmune diseases with overlapping clinical symptoms, complicating accurate diagnosis. This study leverages integrative machine learning of gene expression and DNA methylation data to improve diagnostic precision...

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Autors principals:	Muhammad Mazhar Fareed, Sergey Shityakov
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-01-01
Col·lecció:	In Silico Research in Biomedicine
Matèries:	Systemic lupus erythematosus Primary Sjögren’s syndrome Machine learning Gene expression DNA methylation diagnostic biomarkers
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S3050787125001222
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