Integrative machine learning of gene expression and DNA methylation for the accurate diagnosis of systemic lupus erythematosus and Sjögren’s syndrome

Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSjS) are systemic autoimmune diseases with overlapping clinical symptoms, complicating accurate diagnosis. This study leverages integrative machine learning of gene expression and DNA methylation data to improve diagnostic precision...

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Detalhes bibliográficos

Principais autores:	Muhammad Mazhar Fareed, Sergey Shityakov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-01-01
Colecção:	In Silico Research in Biomedicine
Assuntos:	Systemic lupus erythematosus Primary Sjögren’s syndrome Machine learning Gene expression DNA methylation diagnostic biomarkers
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S3050787125001222
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