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Inhibition of insulin‐like growth factor 2 mRNA‐binding protein 1 sensitizes colorectal cancer cells to chemotherapeutics

Abstract Although colorectal cancer (CRC) treatment has seen a remarkable improvement in the recent years, many patients will develop metastasis due to the resistance of cancer cells to chemotherapeutics. Targeting mechanisms driving the resistance of CRC cells to treatment would significantly reduc...

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Principais autores: Nicole Betson, Mohammed Hajahmed, Tsige Gebretsadek, Kenneth Ndebele, H. Anwar Ahmad, Paul B. Tchounwou, Vladimir S. Spiegelman, Felicite K. Noubissi
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-12-01
coleção:FASEB BioAdvances
Assuntos:
5‐FU
chemotherapeutics
CRC
IGF2BP1
irinotecan
oxaliplatin
Acesso em linha:https://doi.org/10.1096/fba.2021-00069
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