IGF2BP family of RNA-binding proteins regulate innate and adaptive immune responses in cancer cells and tumor microenvironment

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BP1, IGF2BP2, and IGF2BP3) are a family of RNA-binding proteins that play an essential role in the development and disease by regulating mRNA stability and translation of critical regulators of cell division and metabolism. Genetic and chemical...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Irina A. Elcheva, Chethana P. Gowda, Daniel Bogush, Svetlana Gornostaeva, Anna Fakhardo, Neil Sheth, Kathleen M. Kokolus, Arati Sharma, Sinisa Dovat, Yasin Uzun, Todd D. Schell, Vladimir S. Spiegelman
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-07-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	IGF2BP/IMP RNA-binding protein (RBP) interferon-stimulated genes (ISGs) melanoma leukemia anti-PD-1
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224516/full
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