Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1

Summary: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a progressive disease with only one approved treatment currently available. Hepatic phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme of the serine biosynthesis pathway, regulates MAFLD development. However, the...

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Үндсэн зохиолчид:	Penghui Hu, Xiao Shan, Hongyuan Dong, Sujun Yu, Baochen Wang, Hui Xiong, Zemin Ji, Weijia Jing, Yan Cui, Zihan Li, Yanzhao Zhou, Zhe Wang, Jinrong Wang, Jiuzhou Tang, Ting Wang, Keliang Xie, Qiujing Yu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2025-03-01
Цуврал:	Cell Reports
Нөхцлүүд:	CP: Metabolism CP: Immunology
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124725001974
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!