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A computational approach to identify point mutations associated with occult hepatitis B: significant mutations affect coding regions but not regulative elements of HBV

<p>Abstract</p> <p>Background</p> <p>Occult Hepatitis B Infection (OBI) is characterized by absence of serum HBsAg and persistence of HBV-DNA in liver tissue, with low to undetectable serum HBV-DNA. The mechanisms underlying OBI remain to be clarified. To evaluate if specific point mutations of HBV...

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Hlavní autoři: Presti Alessandra, Tritarelli Elena, Villano Umbertina, Amadori Alessandra, Marcantonio Cinzia, Prosperi Mattia, Bruni Roberto, Ciccozzi Massimo, Ciccaglione Anna R
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2011-08-01
Edice:Virology Journal
Témata:
Hepatitis B Virus
occult infection
bioinformatics
On-line přístup:http://www.virologyj.com/content/8/1/394
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