An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones

<p>Abstract</p> <p>Background</p> <p>Infections with hepatitis C virus (HCV) progress to chronic phase in 80% of patients. To date, the effect produced by HCV on the expression of microRNAs (miRs) involved in the interferon-β (IFN-β) antiviral pathway has not been explored in details. Thus, we compa...

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Hauptverfasser:	Villano Umbertina, Costantino Angela, Stellacci Emilia, Tataseo Paola, Tritarelli Elena, Marcantonio Cinzia, Bruni Roberto, Battistini Angela, Ciccaglione Anna
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2011-10-01
Schriftenreihe:	BMC Genomics
Online-Zugang:	http://www.biomedcentral.com/1471-2164/12/485
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