Ex vivo engineering of phagocytic signals in breast cancer cells for a whole tumor cell-based vaccine

Abstract Background Today, cell therapies are constantly evolving and providing new options for cancer patients. These therapies are mostly based on the inoculation of immune cells extracted from a person’s own tumor; however, some studies using whole tumor cell-based vaccines are approaching the le...

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Autori principali: Román Martí-Díaz, Luis Sánchez-del-Campo, María F. Montenegro, Trinidad Hernández-Caselles, Antonio Piñero-Madrona, Juan Cabezas-Herrera, José Neptuno Rodríguez-López
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-07-01
Serie:BMC Cancer
Soggetti:
Breast cancer
Whole tumor cell-based vaccines
CD47
Ionizing radiation
Anti-tumor immunity
Accesso online:https://doi.org/10.1186/s12885-025-14432-1
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