Relevance of stereotyped B-cell receptors in the context of the molecular, cytogenetic and clinical features of chronic lymphocytic leukemia.

Highly homologous B-cell receptors, characterized by non-random combinations of immunoglobulin heavy-chain variable (IGHV) genes and heavy-chain complementarity determining region-3 (HCDR3), are expressed in a recurrent fraction of patients affected by chronic lymphocytic leukemia (CLL). We investig...

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Principais autores:	Francesco Maura, Giovanna Cutrona, Sonia Fabris, Monica Colombo, Giacomo Tuana, Luca Agnelli, Serena Matis, Marta Lionetti, Massimo Gentile, Anna Grazia Recchia, Francesco Di Raimondo, Caterina Musolino, Fiorella Ilariucci, Nicola Di Renzo, Emanuela Pesce, Stefano Molica, Massimo Federico, Agostino Cortelezzi, Fortunato Morabito, Manlio Ferrarini, Antonino Neri
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Acceso en liña:	http://europepmc.org/articles/PMC3163661?pdf=render
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