Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements

Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5+ B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG rearrangements are present in normal B cells...

詳細記述

書誌詳細

主要な著者:	Davide Bagnara, Monica Colombo, Daniele Reverberi, Serena Matis, Rosanna Massara, Niccolò Cardente, Gianluca Ubezio, Vanessa Agostini, Luca Agnelli, Antonino Neri, Martina Cardillo, Stefano Vergani, Fabio Ghiotto, Andrea Nicola Mazzarello, Fortunato Morabito, Giovanna Cutrona, Manlio Ferrarini, Franco Fais
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2022-06-01
シリーズ:	Frontiers in Oncology
主題:	chronic lymphocytic leukemia (CLL) immunoglobulin repertoire B-cells CD5 IGHV somatic mutations Ig light chain
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fonc.2022.894419/full
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!