Target Binding of Black Phosphorus Nanomaterial to Polo‐Like Kinase 1 for Cancer Chemotherapy: A Mutual Selection of Nanomaterial and Protein

ABSTRACT The intrinsic properties of black phosphorus (BP) nanomaterials (NMs) enable them for targeted binding to polo‐like kinase 1 (PLK1), thus inhibiting its kinase activity. However, the mechanism and targeted binding sites underlying this interaction remain unclear. To elucidate the critical p...

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Detalhes bibliográficos

Principais autores:	Fangfang Liu, Zhong‐Da Li, Yanqiao Zeng, Xiaofeng Wang, Yingnan Liu, Qi Li, Wenhe Luo, Xiaoman Suo, Yaqing Xu, Feng Yuan, Dan Zhang, Wuqiong Zhang, Shengyong Geng, Xue‐Feng Yu, Guofang Zhang, Yang Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-12-01
coleção:	Exploration
Assuntos:	black phosphorus nanomaterials PLK family PLK1 inhibitor protein structure targeted interaction of nanomaterial with protein
Acesso em linha:	https://doi.org/10.1002/EXP.20240143
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