Target Binding of Black Phosphorus Nanomaterial to Polo‐Like Kinase 1 for Cancer Chemotherapy: A Mutual Selection of Nanomaterial and Protein

ABSTRACT The intrinsic properties of black phosphorus (BP) nanomaterials (NMs) enable them for targeted binding to polo‐like kinase 1 (PLK1), thus inhibiting its kinase activity. However, the mechanism and targeted binding sites underlying this interaction remain unclear. To elucidate the critical p...

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Hauptverfasser:	Fangfang Liu, Zhong‐Da Li, Yanqiao Zeng, Xiaofeng Wang, Yingnan Liu, Qi Li, Wenhe Luo, Xiaoman Suo, Yaqing Xu, Feng Yuan, Dan Zhang, Wuqiong Zhang, Shengyong Geng, Xue‐Feng Yu, Guofang Zhang, Yang Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2025-12-01
Schriftenreihe:	Exploration
Schlagworte:	black phosphorus nanomaterials PLK family PLK1 inhibitor protein structure targeted interaction of nanomaterial with protein
Online-Zugang:	https://doi.org/10.1002/EXP.20240143
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