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A genome‐scale yeast library with inducible expression of individual genes

Abstract The ability to switch a gene from off to on and monitor dynamic changes provides a powerful approach for probing gene function and elucidating causal regulatory relationships. Here, we developed and characterized YETI (Yeast Estradiol strains with Titratable Induction), a collection in whic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yuko Arita, Griffin Kim, Zhijian Li, Helena Friesen, Gina Turco, Rebecca Y Wang, Dale Climie, Matej Usaj, Manuel Hotz, Emily H Stoops, Anastasia Baryshnikova, Charles Boone, David Botstein, Brenda J Andrews, R Scott McIsaac
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Nature 2021-06-01
Schriftenreihe:Molecular Systems Biology
Schlagworte:
BAR‐seq
CRISPRi
gene overexpression
yeast genomics
yeast mutant array
Online-Zugang:https://doi.org/10.15252/msb.202110207
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