IGFBP3 induces PD-L1 expression to promote glioblastoma immune evasion
Abstract Background Glioblastoma (GBM) characterized by immune escape is the most malignant primary brain tumors, which has strong immunosuppressive effect. Programmed death ligand-1 (PD-L1) is a recognized immunosuppressive member on the surface of tumor cells, and plays a crucial role in immune ev...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2024-02-01
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| Schriftenreihe: | Cancer Cell International |
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| Online-Zugang: | https://doi.org/10.1186/s12935-024-03234-3 |
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