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HucMSC-derived exosomes alleviate inflammatory bowel disease via upregulating FXR to suppress macrophage ferroptosis

Abstract Inflammatory bowel disease (IBD) is a chronic intestinal disorder characterized by excessive inflammation and intestinal damage. Known for its chronic and relapsing nature, IBD currently lacks curative pharmacological therapies. Herein, we investigated the therapeutic potential of human umb...

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Bibliografiske detaljer
Principais autores: Yuxuan Xia, Ting Sun, Mengjiao Zhou, Bo Wang, Fei Mao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-04-01
Serier:Biology Direct
Fag:
Online adgang:https://doi.org/10.1186/s13062-026-00820-5
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