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HucMSC-derived exosomes alleviate inflammatory bowel disease via upregulating FXR to suppress macrophage ferroptosis

Abstract Inflammatory bowel disease (IBD) is a chronic intestinal disorder characterized by excessive inflammation and intestinal damage. Known for its chronic and relapsing nature, IBD currently lacks curative pharmacological therapies. Herein, we investigated the therapeutic potential of human umb...

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Hlavní autoři: Yuxuan Xia, Ting Sun, Mengjiao Zhou, Bo Wang, Fei Mao
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2026-04-01
Edice:Biology Direct
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On-line přístup:https://doi.org/10.1186/s13062-026-00820-5
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