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A three‐range approach enhances the prognostic utility of CSF biomarkers in Alzheimer's disease

Abstract Introduction Alzheimer's disease consensus recommends biomarker dichotomization, a practice with well‐described clinical strengths and methodological limitations. Although neuroimaging studies have explored alternative biomarker interpretation strategies, a formally defined three‐range appr...

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Asıl Yazarlar: Wagner S. Brum, Marco Antônio deBastiani, Andrei Bieger, Joseph Therriault, João P. Ferrari‐Souza, Andréa L. Benedet, Paramita Saha‐Chaudhuri, Diogo O. Souza, Nicholas J. Ashton, Henrik Zetterberg, Tharick A. Pascoal, Thomas Karikari, Kaj Blennow, Pedro Rosa‐Neto, Eduardo R. Zimmer, Alzheimer's Disease Neuroimaging Initiative (ADNI)
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2022-01-01
Seri Bilgileri:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Konular:
Alzheimer's disease
CSF biomarkers
cut‐points
prognostic modeling
three‐range
Online Erişim:https://doi.org/10.1002/trc2.12270
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