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Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.

Rheumatoid arthritis is an auto-immune disease of the synovial joints, hallmarked by chronic inflammation and subsequent progressive tissue destruction. TYRO3, AXL and MER (gene name Mertk) (TAM) receptors are part of a negative feedback signaling system in the immune reaction and mediate efferocyto...

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書誌詳細
主要な著者: Claire E J Waterborg, Marije I Koenders, Peter L E M van Lent, Peter M van der Kraan, Fons A J van de Loo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2018-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://doi.org/10.1371/journal.pone.0205902
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